To get started with your Ledger hardware wallet, go to ledger.com/start. The website provides a comprehensive guide for setting up your device. Begin by unboxing your Ledger wallet and ensuring all components are present. Connect your device to your computer or smartphone and download the Ledger Live application. Follow the on-screen instructions to initialize your wallet, create a new account, and set up a secure PIN. Make sure to back up your recovery phrase in a safe place. Once set up, you can use Ledger Live to manage your cryptocurrencies and monitor your assets securely.